{"created":"2023-05-15T11:34:31.651878+00:00","id":849,"links":{},"metadata":{"_buckets":{"deposit":"e85e40d3-74d6-4721-88ea-c772ac84a665"},"_deposit":{"created_by":2,"id":"849","owners":[2],"pid":{"revision_id":0,"type":"depid","value":"849"},"status":"published"},"_oai":{"id":"oai:cur-ren.repo.nii.ac.jp:00000849","sets":["2:5:26"]},"author_link":["5252","5253","5254","5250","5249","5251"],"item_10002_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-06-16","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"151","bibliographicPageStart":"147","bibliographicVolumeNumber":"9","bibliographic_titles":[{"bibliographic_title":"中国学園紀要"},{"bibliographic_title":"Journal of Chugokugakuen","bibliographic_titleLang":"en"}]}]},"item_10002_description_5":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ヒト口腔癌HSC4細胞を使用し，細胞動態に対するビスコクラウリン型アルカロイド(セファランチン)(CEP)の作用を検討した。　\n１　比例増殖中の細胞は倍加時間36時間で，その細胞周期分画はほぼ一定であリ，Ｇ１期18.5時間，Ｓ期12.4時間Ｇ２/Ｍ期3.1時間であった。　\n２　比例増殖中の細胞にCEPを添加し，細胞増殖に及ぼす影響を観察した。CEP(１μg)では細胞増殖がゆっくりとCEP(５μg)では急激に抑制された。　\n３　CEP(１μg)の抑制を解除すると24時間後には２倍以上に細胞が増殖することが観察された。　\n４　比例増殖中の細胞にCEP(１μg)を添加し細胞周期の分画の変化を観察した。CEPを添加するとＧ１期分画がゆっくりと増加し，Ｓ期，Ｇ２/Ｍ期が減少した。\n５　比例増殖中の細胞にCEP(５μg)を添加するとＧ１期分画が急激に増加し，Ｓ期，Ｇ２/Ｍ期が減少した。\n　以上のことからHSC4細胞へのCEPの作用について考察した。","subitem_description_type":"Abstract"}]},"item_10002_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"中国学園大学/中国短期大学"}]},"item_10002_rights_15":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"中国学園大学/中国短期大学"}]},"item_10002_source_id_11":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11806598","subitem_source_identifier_type":"NCID"}]},"item_10002_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1347-9350","subitem_source_identifier_type":"ISSN"}]},"item_10002_subject_21":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"460","subitem_subject_scheme":"NDC"}]},"item_10002_text_24":{"attribute_name":"出版者（英）","attribute_value_mlt":[{"subitem_text_language":"en","subitem_text_value":"Chugokugakuen University / Chugoku Junior Cllege"}]},"item_10002_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松石, 嘉織"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"松野, 瞳美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"川﨑, 祥二"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuisi, Kaori","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuno, Hitomi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawasaki, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-10-03"}],"displaytype":"detail","filename":"009_147_152.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"009_147_152.pdf","url":"https://cur-ren.repo.nii.ac.jp/record/849/files/009_147_152.pdf"},"version_id":"a0036ab5-34a4-4491-8a4f-5b2d7a9d6851"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"培養細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"増殖","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞周期","subitem_subject_scheme":"Other"},{"subitem_subject":"HSC4","subitem_subject_scheme":"Other"},{"subitem_subject":"セファランチン","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ヒト培養細胞(HSC4)の増殖に及ぼすビスコクラウリン型アルカロイド(セファランチン)の影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒト培養細胞(HSC4)の増殖に及ぼすビスコクラウリン型アルカロイド(セファランチン)の影響"},{"subitem_title":"Effect of Cepharanthine on the Growth of Human Culture Cell Lines (HSC4)","subitem_title_language":"en"}]},"item_type_id":"10002","owner":"2","path":["26"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-10-03"},"publish_date":"2018-10-03","publish_status":"0","recid":"849","relation_version_is_last":true,"title":["ヒト培養細胞(HSC4)の増殖に及ぼすビスコクラウリン型アルカロイド(セファランチン)の影響"],"weko_creator_id":"2","weko_shared_id":-1},"updated":"2023-05-15T17:57:05.876231+00:00"}